However, it is safe to consult with a health expert about the risk while taking statins and grapefruit together or even avoid taking statins with grapefruit juice. Recent studies on grapefruit and statins interaction suggest that moderate grapefruit consumption can be compatible with taking statin drugs. For people who take statins and grapefruit on the same day, it could cause side effects. The interaction that occurs when grapefruit and statins are taken together differs from person to person. Thus, it is safe to take medication through an injection, to avoid grapefruit interaction. The interaction between grapefruit and medications poses side effects only when the medication is taken orally as the interaction occurs in the digestive tract. This is an issue only for atorvastatin and simvastatin and is only problematic at the highest dosages." According to a study published in the British Medical Journal, the drug interaction is strong only with two types of statins - simvastatin (Zocor) and atorvastatin (Lipitor).ĭr Steven Nissen, Cardiologist and Cardiovascular Medicine Department Chair at Cleveland Clinic's Heart and Vascular Institute, said, "Only certain statin medications interact negatively with grapefruit. However, not all statins interact the same way with grapefruit. Drugs that are used to treat nausea, urinary tract infections, heart conditions, immunosuppressants and anxiety drugs interact with grapefruit. Some people report sleep problems while taking statins. People over 65 years of age and women are at a higher risk for side effects from statins.Īs many as 85 prescription drugs interact with grapefruit. Other side effects reported by people taking statins include: weakness. Statins cause other side effects such as muscle and joint pain, increased blood sugar, digestive disorders, and neurological side effects, including memory loss and confusion. According to a report by the Food and Drug Administration, the interaction increases the risk of muscle breakdown, kidney failure and liver damage. The interaction of grapefruit and statins increases the side effects of the drugs.
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